This problem is a CINT problem reported to Masa.
A turnaround is to replace your statement:
    s->Fill(-1,10) 
by
    Float_t x=-1;
    Float_t y=10;
    s->Fill(x,y);
Numeric values seem to give problems to CINT in case the called
member function has a prototype involving a double precision
argument. This is the case for TProfile::Fill (2 prototypes
with 2 and 3 parameters).
Rene Brun
> FILE: test.C
> {
>         TProfile *s = new TProfile ("my", "good", 16, -4, 0, 0, 20);
>         s->Fill (-1,10);
>         printf ("Just did the first fill, will now try the second");
> #include "test1.C"
>         test1 junk1;
> }
> 
> -----------
> FILE: test1.C
> class test1 {
> public:
>         test1 (void);
> };
> 
> test1::test1 (void)
> {
>         TProfile *j = new TProfile ("hi", "there", 16, -4.0, 4.0, 0, 20);
>         j -> Fill (10, 20);
> }